Dynamical effects of diffusive cell coupling on cardiac excitation and propagation: a simulation study

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Dynamical effects of diffusive cell coupling on cardiac excitation and propagation: a simulation study.

Cell coupling is considered to be important for cardiac action potential propagation and arrhythmogenesis. We carried out computer simulations to investigate the effects of stimulation strength and cell-to-cell coupling on action potential duration (APD) restitution, APD alternans, and stability of reentry in models of isolated cell, one-dimensional cable, and two-dimensional tissue. Phase I fo...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Heart and Circulatory Physiology

سال: 2004

ISSN: 0363-6135,1522-1539

DOI: 10.1152/ajpheart.00299.2004